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Reimagining Medicine

Company overview Financial review 2023 priorities Appendix Solid Q4 and FY performance Group1 USD million Q4 Change vs. PY 2022 FY 2022 % USD % cc % USD Change vs. PY % cc Net Sales 12,690 -4 3 50,545 -2 4 Core Operating income 4,030 6 15 16,665 0 8 Operating income 1,949 -24 -14 9,197 -21 -13 Net Income 1,466 -91 -90 6,955 -71 -67 Growth ex. prior year Roche income -12 2 -20 -9 Core EPS (USD) 1.52 9 19 6.12 -3 0 Growth ex. prior year Roche income 12 23 5 14 EPS (USD) 0.69 -91 -89 3.19 -70 -66 Growth ex. prior year Roche income -8 7 -17 -7 Free Cash Flow 3,552 17 11,945 -10 Growth ex. prior year Roche dividend 17 -6 FINANCIAL PROFILE 1. Core results, constant currencies and free cash flow are non-IFRS measures. Further details regarding non-IFRS measures can be found starting on page 50 of the Condensed Financial Report. A table showing the Q4 2022 and FY 2022 key figures excluding Roche can be found on page 3 and 9 and a reconciliation of 2021 IFRS results and non-IFRS measures core results to exclude the impacts of the 2021 divestment of our Roche investment can be found on page 59 of the Condensed Interim Financial Report. 37 Investor Relations | Q4 2022 Results āœ“ NOVARTIS | Reimagining Medicine
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