Investor Presentaiton

IJMS II COIMAMA INTERNATIONAL JOURNAL of MEDICAL STUDENTS Abstracts Abstracts 44 Bioprospecting Species of Vegetable Leaves Himatanthus Drasticus (Janaúba) Gizelli Santos Lourenço Coutinho; Tarciano Nascimento Perei- ra; Luiz Mario da Silva Silveira; Antonio Carlos Romão Borges; Marilene Oliveira da Rocha Borges; Roberto Sigfrido Gallegos Olea Introduction: In Maranhão, the extraction of Himatanthus drasticus (janaúba) has gained importance as an alternative income for the population, but few studies are found in the literature on the lea- ves of this species. Objectives: This study aims to determine the phytochemical composition and metal, as well as evaluating the an- tioxidant and microbiological activity of the hydroalcoholic extract of the leaves of the plant species Himatanthus drasticus. Methods: qualitative tests were performed for detection of secondary metabo- lites and minerals detection was performed through atomic absorp- tion (ICP-OES technique). In relation to the antioxidant activity was used the method in vitro with DPPH and antimicrobial activity were used standard strains (ATCC) of gram-positive bacteria (Staphylococ- cus aureus, Streptococcus agalacicus), gram-negative (Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Proteus mirabi- lis), and yeasts of the genus Candida (C. albicans, C. parapsilosis, C. tropicallis, C. glabrata) by diffusion tests in a solid medium and in an agar diffusion, by determining the Minimum Inhibitory Concentra- tion (MIC). Results: We found in the leaves of Himatanthus drasticus flavonoids, condensed tannins, alkaloids, free steroids, triterpenes, saponins, resins, coumarins and predominance of minerals like cal- cium, potassium, phosphorus and magnesium. The antioxidant ac- tivity showed EC50 of 31.62 mg/mL, and the antimicrobial activity was no inhibition of all tested strains at a MIC 15% by agar dilution technique. Conclusion: These results are preliminary data, about the plant species Himatanthus drasticus, however further studies should be conducted to better clarification on the use of this specie by Maranhão population. 45 Survey of Greater Herbal Medicines Marketing in one drugs- tore of São Luís, Maranhão, Brazil Tarciano Nascimento Pereira; Renatta Belfort de Souza; Nilton Boaes Barbosa; Josefa Cristina da Silva Tavares; Rosália Mo- reira dos Santos; Gizelli Santos Lourenço Coutinho Introduction: Herbal constitute a form of complementary or alternati- ve therapy in the face of health needs. They are presented as an al- ternative to substitute or complement of synthetic drugs. Objectives: This study aimed to carry out the survey of herbal medicines sold in a drugstore in the capital of Maranhão. Methods: It constitutes a survey of the main herbal medicines consumed by the population from September 2014 to March 2015. Results: Being herbal sold in 2297, with higher sales for the months of December (17.3%), March (16.6%) to January (16%). Thus, when stratifying herbal more acqui- red according to the plant drug, it was observed that the Cynara sco- lymus and associations Peumus boldus were the most sought after, representing 54.11%. Then, Peumus boldus (23.9%), Mikania glome- rata (6.75%), Hedera helix (4.8%), Papaver somniferum (2.52%), Cor- dia verbanacea (1.43%), Aesculus hippocastanum (0.74%), Ginkgo bi- loba (0.71%), purple passionflower (0.65%) and others (4.39%) as the best-selling herbal medicines in the pharmaceutical establishment. The most dosage forms were dispensed oral solution (78.5%), syrup (9.14%), capsule (3%), elixirs (2.52%), tablet (2.09%), gum (1.22 %) and others (3.5%). Conclusion: Although the study has taken into consideration only one drugstore, presented important results so that they assess the consumption of herbal for the population of São Luís, indicating a prevalence of sale of herbal medicines for digestive and respiratory disorders. 46 Organization of Primary Care Units' Records in Brazil Renato Albuquerque Heluy; Maria Teresa Soares De Britto E Alves Introduction: The information's recording about the patient is called medical chart. It should consist of identification, medical history, physical examination, definitive diagnosis and treatment. It is es- sential for judicial protection for the health professional, allowing communncation among professionals and support public manage- ment strategies. This study evaluates the registration data, organi- zation and use of medical records in primary care units. Objectives: To check the recording quality in primary care service charts and to estimate the rate of electronic chart's use. Methods: Cross-sectional study that used Access and Quality of Primary Care Improving Pro- gram (PMAQ-AB) data base. Information obtained by interviewing 17.202 teams of heath care units professionals and 4 users of each unit in 2012. This study uses the second module of PMAQS instru- ment called services organization, teamwork process and access of primary care units. It used the program Stata 12.0 to compare pri- mary care units services' quality among Brazil's geographic regions. It was used Chi-squared distribution test to evidence differences in estimated rates. It was considered relevant diferences with p value , 0,05. Results: South region presented the highest rate of eletronic chart implantation, with 30.35%. Of this total, 84.35% had the chart integrated with others attention care points. In Northeast, only 1.33% had eletronic chart implanted. The variable "readable letter", North reagion showed the highest rate, with 82.87%, while South showed the lowest one, with 70.06%. A 9.10% rate at Southeast did not have users' identification (name, age, sex) registered. This rate at North region was 96.94%. Conclusion: It is noticed the small use of eletro- nic charts all over the country. This resource prove itself effective for users data's register and integration among primary care units. Therefore, its use must be encouraged by heath managers. Rates of charts without users' identification are noteworthy, showing charts' filling's bad quality. That point can be improved by adopting a model standard register. Registering with readable letter was a frequent action in every region. 47 Epidemiological profile in Tuberculosis in Altos-Piaui Layanne Cavalcante De Moura; Giovana Brandão Veneziani; Ivo Belarmino Souza Silva; Anelis De Sousa Martins Freitas; Karla Késsia Portela Silva Soares; Joana Elisabeth De Sousa Martins Freitas Introduction: Even with current advances in medicine, tuberculosis (TB) remains a public health problem due to a high prevalence of morbidity and mortality. Objectives: This study has characterized the epidemiological profile of the reported tuberculosis cases in the city of Altos-Piauí between 1998 and 2012. Methods: This was a retrospective, descriptive, quantitative and exploratory cohort study whose data were obtained by the City Health Department having as variables the frequency of occurrence of cases, gender, age, diag- nostic investigation, entry data, clinical presentation and the cases outcome. The data were organized and analyzed using Microsoft Office Excel 2010 spreadsheets. The research was approved by the Ethics Committee of the Faculty Integral Differential under the Proto- col 17968514.2.0000.5211 and authorized by faithful term depositary by the institution where the research took place. Results: During the study period, 215 cases were reported, with an average of 14 per year. It showed a male dominance with 63.26% and cases in the age group of 41-50 years (20%). Among the tests performed to contribute and define the diagnosis of TB, 174 (80.93%) were sputum smear, 155 (72.09%) Chest RX, 19 (8.84%) histopathology, 12 (5.58%) the Mantoux tuberculin skin test and 2 (0.93%) were culture. Regarding how it was presented, 172 (86.05%) cases were initial treatment, 28 (13.02%) relapse treatment, 2 (0.93%) pictured after the abandon- ment. Among the types of TB, the pulmonary positive type presented with 107 (49.76%), negative pulmonary type with 79 cases (36.74%) the lymph node type with 10 (4.65%), followed by 8 cases of pleural type (3.72%). The cure rate was 177 (82.3%) followed by 15 (6.98%) deaths; 13 (6.05%) were transferred to another health service; and there was 7 (3.26%) cases of abandonment. Conclusion: This study was characterized by the trend of lessening cases, predominantly in men between 21-50 years old and were submitted to sputum smear, as well as new cases, pulmonary type and discharged as cured. It is hoped that the results presented serve as an exemple of a basis for greater control of the disease contributing to the identification of risk groups and the Program's weak points with a consequent decrease in the incidence of tuberculosis in Altos - Piaui. 48 Occurrence of viral hepatitis in Maranhão from 2007 to June 2015 Rute Rocha Santos; Lizandra Murielle de Carvalho Moraes; Milla Dantas Martins Rodrigues Xavier; Marcela Bezerra Mar- ques; Natália Maria Marques Brito; Jarbas Moura Moraes Introduction: Viral hepatitis are caused by diferente etiological agents who share the hepatotropism. The prevention of these hepatitis is a major challenge for the countries public health and for the medical and scientific communities. Therefore, hepatitis viruses cause signifi- cant morbidity and mortality in the world, causing acute and chronic liver disease. Objectives: To analyze the occurrence of viral hepatitis in Maranhão from 2007 to June 2015. Methods: This is an epidemio- logical quantitative study prepared from viral hepatitis related data, which was removed from the Notifiable Diseases Information System (SINAN). The data was analyzed according to the etiologic classifica- tion, age, clinical form and sex. The graphs and tables were made in Microsoft Office Excel 2014. Results: This is an epidemiological quan- titative study prepared from viral hepatitis related data, which was removed from the Notifiable Diseases Information System (SINAN). The data was analyzed according to the etiologic classification, age, clinical form and sex. The graphs and tables were made in Microsoft Office Excel 2014. Conclusion: Based on the data, it was noted that the incidence of viral hepatitis between 2007 and June 2015 in Ma- ranhão prevailed in isolation form of hepatitis A, in the age group of 20-39 years, in males. Furthermore, it was observed that the majority of cases were presented in the clinical form of acute hepatitis. 49 Pharmaceutical Care in Accident Prevention with Toxic Plants in the city of São Luís - MA, Brazil Tássio Rômulo Silva Araújo Luz; José Antonio Costa Leite; Daniela Patrícia Brandão Silveira; Maria Cristiane Aranha Brito; José Wilson Carvalho de Mesquita; Denise Fernandes Coutinho Moraes Introduction: Many plants have toxic substances that can cause da- mage to health. According to the National System of Toxic-Pharmaco- logical Information (SINITOX) of FIOCRUZ, 60% of cases of poisoning by toxic plants in Brazil occur in children under 9 years, of which 80% are accidental. Objectives: Evaluate the knowledge of munici- pal school students in São Luís MA about toxic plants, as well as educate about preventive measures to accidents. Methods: This is an experience report of students Phytotherapy Program / UFMA, organized from information on toxic plants obtained during lectu- res to elementary school students from public schools in São Luís - MA on herbal medicine. During the lectures, 10 toxic plants were presented: no one beats me, Castor, Aveloz, Cassava-Brava, Purple Pinion, Nettle, Tinhorão, Crown of Christ, St. George Sword and hat of Napoleon and evaluated the knowledge and ease of obtaining. Because it is teaching-learning experience, there was no need for the formalization of the free and informed consent procedure. Results: During the study, it was observed that 63% of students had easy access to some toxic plants presented, at home, on the street or at school; 92.5% were unaware of the toxicity of at least 3 of the listed toxic plants, the most cited were Me-No-Can, Tinhorão and Castor. The Nettle and hat of Napoleon plants were the best known of the students. No one beats me and Aveloz have ornamental employment , which intensifies the risk of accidents by ingestion or contact with parts of these plants, especially by children. Another factor related to poisoning is the common idea that "If comes from nature does not hurt," excluding the possibility of a plant causing any damage to health, which makes it important demystify this concept. To prevent such accidents educational activities were held, informing about the toxicity of these plants and first aid measures. Conclusion: It was found that the lack of knowledge of toxic plant species, as well as its ease of access are the main factors related to the occurrence of intoxication. In this context, it is believed that the best way to prevent accidents is the spread of knowledge about toxic species in educational programs for the population, contributing to the reduc- tion of accidents with them. 50 Pharmacotherapeutic follow-up in Diabetic and Hypertensive Patient Tássio Rômulo Silva Araújo Luz; José Antonio Costa Leite; Maria Luiza Cruz Introduction: Diabetes is a metabolic disorder characterized by high blood glucose due to insulin deficiency, often associated with its re- sistance. In hypertension, have increased blood pressure, which is a risk factor for cardiovascular disease. As a result, the pharmaceutical care is a essential tool for pharmacotherapeutic follow, especially in diabetic hypertensive patients who require special care involving dose regimen, proper storage of medications and changes in lifes- tyle. Objectives: This study aimed to follow a diabetic and hyperten- sive patient on polytherapy, trying to detect drug-related problems, seeking alternatives that improve their quality of life. Methods: The Monitoring was employed method Dader, which occurred: offering service, first interview, study phase, intervention phase and evalua- tion of results. Results: Male, 58, 178 cm, 80 kg, diabetic for 25 years, and hypertense for 16 years, with joint pain and stomach. In the assessment of vital signs, the only finding was hypertension, due the constant high blood pressure (150/100 mmHg). At the anthro- pometric measurements it was found that the patient has a BMI> 25 (overweight) and high waist circumference (100 cm), increasing risk of metabolic complications. Laboratory tests of glucose profile (glu- cose, HbA1c and postprandial glucose) are changed, even ith the use of drugs. As for habits, the patient reported consuming alcohol on weekends and suspending the medication. The patient used: gliben- clamide, omeprazole, Metformin hydrochloride, Hidrochlorothiazide, Losartan Potassium, Aspirin. Was found drug interactions of clinical importance and it was found that the patient had difficulty to use the medication, featuring non-adherence to treatment. For resolu- tion, there were pharmaceutical interventions, producing a moni- toring diary, a booklet of recommendations, one pharmacotherapy guide and a cabinet medicines indicating a more practical way the correct way to use them. Conclusion: With the pharmacotherapeutic follow-up, the patient was able to improve their quality of life, could solve all your doubts and be guided not only on the use of medici- nes, but also in habits that can be changed. 51 Epidemiological Profile of Schistosomiasis Mansoni in Nor- theast 2010-2015 Marcela Bezerra Marques; Layane Duarte Silva; Thájara Fer- nandes De Sá Guimarães; Augusto César Evelin Rodrigues Introduction: Schistosomiasis is a typical northeastern endemic pa- rasitic disease which remains a serious problem of public health.1 Also known as water belly, schist or snail disease, is characterized in the most severe form, hepatosplenic at enlarged liver and spleen. Diagnosis and treatment are relatively simple, but the eradication of the disease is only possible with preventive measures. Objecti- ves: Raise an epidemiological profile of Schistosomiasis mansoni in the Northeast region 2010 to 2015. Methods: This is a retrospective epidemiological quantitative study compiled from data from the No- tifiable Diseases Information System (SINAN). We analyzed all schis- tosomiasis data regarding age, gender, education and development of the disease in the Northeast region 2010 to 2015. The graphs and tables were made in Microsoft Office Excel 2014. Results: We reported 7298 cases of schistosomiasis in the Northeast, and 3974 (54.5%) male and 3323 (45.5%) in females. Of all cases, the largest num- ber occurred in BA with 3787 cases (51.9%), followed by PE in 1650 (22.6%). The year with the highest occurrence was in 2011, totaling 1526 (20.9%) cases, including the most concentrated in Bahia with 749 (49.1%) cases this year. Most evolved to cure with 3347 patients (45.9%), followed by 185 cases (2.5%) rated as not cure; there were 141 deaths from schistosomiasis, which predominated in the PE (91 cases). The highest frequency occurred in the age group of 20-59 years with 4618 cases (63.3%), followed by people aged less than 20 years with 1625 cases (22.3%). Analyzing the levels of education, 2701 cases were ignored or white and 543 corresponding to illiterate. The highest incidence occurred in people with education level limi- ted to primary education with 2858 cases (39.2%); there was inter- mediate occurrence in people from high school with 863 (11.8%) and lower incidence in those in higher education with 122 cases (1.7%). S28 INTERNATIONAL JOURNAL of MEDICAL STUDENTS www.ijms.info • 2015 Vol 3 Suppl 1 www.ijms.info . 2015 Vol 3 Suppl 1 INTERNATIONAL JOURNAL of MEDICAL STUDENTS II COIMAMA S29