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Investor Presentaiton

77 Investor presentation Full year 2022 Oral amycretin entered phase 1 in Q2 2022, combining protein. and peptide expertise with oral technology Amycretin is a GLP-1 and amylin receptor co-agonist intended for oral delivery Phase 1 single dose and multiple dose trial for oral amycretin in obesity initiated in 2022 GLP-1 receptor Novo NordiskⓇ People living with obesity, and Multiple ascending dose cohorts overweight or otherwise Single ascending dose cohorts healthy Trial objectives Amylin receptor • Assess the safety and tolerability of oral amycretin • Assess PK profile and explore PD effects Utilising the SNAC technology PK: Pharmacokinetics; PD: Pharmacodynamics Trial initiation • Phase 1 was initiated in Q2 2022
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