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Investor Presentaiton

Targeting Growth in Biohubs Targeted initiatives in key biohubs to capture biotech and academic share gains and growth Targeted Sales Approach Digital Experience Portfolio Expansion Charles River Laboratories (CRL) ☐ ☐ • Agile commercial structure to access clients around academic/biotech lab spinout phase Example: >240 biotechs spun out of 130 academic 'foundation' labs in Massachusetts over last 5 years Enhance pull-through across different business units including Discovery Services, Cell Solutions, and C&GT CDMO Enhanced use of e-commerce to achieve 'persona-centric' digital experiences Drive scientific-rich content and client-centric apps to promote market penetration and exposure of biohub clients across multiple businesses Increased capacity and portfolio expansion in GEMS, CRADL TM, and immunodeficient models to better support this client base, which is more C&GT focused 6
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