Investor Presentation H1 2023

46 Investor presentation First six months of 2023 Novo Nordisk has 54% of the global GLP-1 market, while GLP-1 penetration of diabetes volume varies across regions 80% 60% 40% 20% 0% GLP-1 market growth and Novo Nordisk market share May 2020 Novo NordiskⓇ GLP-1 share of total estimated diabetes prescriptions¹ is 5% Million prescriptions¹ 250 70% 68% 200 54% Global: 1% 53% 150 100 50 0 May 2018 2023 NN market share -Market growth NN share of growth NN growth GLP-1 Source: IQVIA MAT value (spot rate), May 2023 SGLT-2i DPP-4i Insulin Global: 5% 2023 Trad. OAD GLP-1 share of estimated diabetes prescriptions 1 The estimated GLP-1 share of prescriptions is based on volume packs from IQVIA. Volume packs are converted into full- year patients/prescriptions based on WHO assumptions for average daily doses or if not available, Novo Nordisk assumptions Source: IQVIA MAT volume (Spot rate), May 2023

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