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Reimagining Medicine

Company overview Financial review 2023 priorities Appendix FINANCIAL PROFILE Sandoz returns to growth in 2022; planned spin-off on track for H2 Driven by Biopharma and ex-US sales FY performance¹ Sales USD 9.2bn (+4%) Biopharma grew 9% and Retail 4% Strong ex-US sales growth: ■ EU: USD 4.9bn (+4%) ■ ROW: USD 2.5bn (+9%) ■ US: USD 1.8bn (-4%) Core Oplnc (-1%) impacted by inflationary pressures on input costs and higher SG&A Key growth drivers for 2023 and beyond Share gains across geographies Two potential US biosimilar approvals expected in H2 2023 Launches, targeting USD 80bn originator sales (2030) with strong pipeline of 15+ biosimilar assets Bolt-on BD&L and M&A On track for planned spin-off in H2 2023 Final transaction requires Novartis AG BoD and shareholder approval Carve-out financials to be provided ahead of CMD Expected to be tax neutral to Novartis and the majority of our institutional shareholders 1. All growth rates in constant currencies (cc). 40 Investor Relations | Q4 2022 Results NOVARTIS | Reimagining Medicine
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