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Investor Presentaiton

Financial Results for Q4 FY2022 ■Marketing Status of GEMTESAⓇ Approx. 190,000 TRx in Q4 FY2022, which is greater than our FY2022 forecast (20% growth vs. Q3 FY2022) +20% ■The market for overactive bladder (OAB) of GEMTESAⓇ is over 400 billion yen/year (gross conversion), and recently expanded by 8% annually* Established broad health plan coverage (Percentage of coverage obtained as of April 2023: total of Medicare Part D lives was approx. 80%, total of commercial lives was >70%) 193,661 161,156 133,949 101,140 65,858 48,299 26,715 6,800 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 FY2021 FY2021 FY2021 FY2021 FY2022 FY2022 FY2022 FY2022 ■Phase 3 study results for OAB associated with benign prostatic hyperplasia will be obtained in 1H FY2023, and sNDA will be submitted in 2H FY2023 Number of prescriptions per quarter with GEMTESA®* *Source IQVIA *NSP sales as of end of Feb. 2023 and TRx as of end of Mar. 2023. Sales for GEMTESAⓇ, MYRBETRIQ, TOVIAZ, and Generics for the 12 months ended Feb. 2023 were $3.1B (130yen/$), which reflects a 8% growth vs 12 months ended Feb. 2022
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