Investor Presentation - First Six Months of 2021 slide image

Investor Presentation - First Six Months of 2021

4 Investor presentation First six months of 2021 Novo Nordisk® Strategic Aspirations 2025 | Highlights first six months of 2021 Purpose and sustainability খ Commercial execution Adding value to society: Initiated Diabetes Compass with the WDF to improve access to diabetes care in low- and middle-income + countries Reaching 15 countries in Changing Diabetes in Children by including Ghana Progress towards zero environmental impact: 45% reduction in CO2 emissions vs the first six months of 2019 and -15% reduction in supplier CO2 emissions Evolve culture and ensure distinct core capabilities: Launch of gender diversity target Diabetes value market share increased by 0.5 percentage point to 29.6%¹ Obesity care sales increased by 34% at CER to DKK 3.5 billion Biopharm sales increased by 7% at CER therapeutic focus Innovation and Financials Diabetes care: Blue indicates developments in Q2 2021 ⚫ OzempicⓇ approved in China • • . Resubmission of semaglutide 2.0 mg in the US Obesity care: Decision to initiate phase 3a development with 50 mg oral semaglutide in obesity Approval of Wegovy TM, semaglutide 2.4 mg, in the US Other serious chronic disease: . • Phase 3a development programmes initiated for treatment of NASH and Alzheimer's Disease Stem cell R&D licence agreement with Heartseed and acquisition of Prothena's ATTR amyloidosis programme Sales growth of 12% and Operating profit growth of 9%: Sales in International Operations grew by 13% Sales in North America Operations grew by 11% and in the US, 56% of sales came from products launched since 2015 Gross margin positively impacted by productivity gains in Product Supply Free cash flow of DKK 32.7 billion and DKK 21.9 billion returned to shareholders The strategic aspirations are objectives that Novo Nordisk intends to work towards and are not a projection of Novo Nordisk's financial outlook or expected growth. Note: Unless otherwise specified growth rates are at constant exchange rates 1 MAT (Moving Annual Total) value market share IO: International Operations; NAO: North America Operations; Sema: Semaglutide; NASH: Non-alcoholic steatohepatitis; FDA: Food and Drug Administration; EMA: European Medicines Agency; GHD: Growth Hormone Deficiency; HFPEF: Heart Failure with preserved Ejection Fraction; WDF: World Diabetes Foundation; R&D: Research and Development; ATTR: Transthyretin Amyloid
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