RSV Seasonal Vaccine Introduction and Growth Strategy slide image

RSV Seasonal Vaccine Introduction and Growth Strategy

Q2 2023 sales £7.1bn¹, +11%¹ Strong commercial execution across all product areas and key medicines Vaccines +15%¹ . Shingrix+20%: another record quarter with continued growth ex-US; now launched in 33 markets, most with <3% penetration ex-US . Bexsero +18% Specialty Medicines +12%1 . Benlysta+19% • Nucala +15% and market leader in IL5 share . Oncology -3% General Medicines +8% Trelegy+30%: best-in-class access with leading US share of voice. ⚫ #1 prescribed SITT2 worldwide in >60 countries Shingrix sales by geography 100% 30% 29% 80% 38% 38% 39% 46% 60% 40% 70% 71% 63% 62% 61% 54% 20% 0% Q1 2022 Q2 2022 Q3 2022 Q4 2022 Q1 2023 Q2 2023 US EU+International HIV +12% Nucala EOS-driven indications driving growth and differentiation • Severe Eosinophilic Asthma Hyper Eosinophilic Syndrome Chronic Rhinosinusitis with Nasal Polyps Eosinophilic Granulomatosis with Polyangiitis Phase III COPD data: H2 2024 Trelegy global sales Sales (£m) 650 550 450 350 250 150 50 2021 2022 2023 Q1 Q2 Q3 Q4 GSK Absolute values at AER; changes at CER, unless stated otherwise 1. Excluding COVID-19 solutions 2. Single inhaler triple therapy 16 10
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