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Investor Presentaiton

40 Investor presentation Full year 2022 The total branded diabetes market has a global value of DKK ~365 billion annually DKK billion Global diabetes market DKK The USA billion +16% +17% 400 367 2021/2022 2020/2021 Growth at CER 200 177 141 150 +34% -12% 90 302 300 100 64 +1% 40 42 50 +35% 31 16 14 20 0 Total Insulin GLP-1 DPP-4i SGLT-2i 200 DKK Outside the USA +39% billion +14% -6% 190 130 200 109 112 161 +41% 100 90 -2% 150 -3% 72 56 53 100 47 69 70 +51% 40 -2% 40 39 +46% 41 50 26 26 0 Total 0 Insulin GLP-1 DPP-4i SGLT-2i Total Insulin GLP-1 DPP-4i SGLT-2i Source: Company announcements as of Q3 2022; 2021/2022 data based on Q4 2021 to Q3 2022 and 2020/2021 data based on Q4 2020 to Q3 2021 Note: The segment value is based on reported figures, whilst the market growth is under constant exchange rate (CER). For Novo Nordisk the diabetes growth includes Insulin and GLP-1, excluding 'other Diabetes care'. Novo NordiskⓇ
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