Roche Pharmaceutical Development and Sales Overview

Geographical sales split by Divisions and Group* CHFM YTD Sep 2021 Pharmaceuticals Division 33,379 YTD Sep 2022 33,189 % change CER 0 United States 16,707 17,199 -1 Europe 6,610 6,100 -1 Japan 3,186 3,029 +7 International 6,876 6,861 0 Diagnostics Division 13,305 13,848 +6 United States 2,845 3,471 +17 Europe 4,851 3,774 -17 Japan 505 691 +55 International 5,104 5,912 +17 Group 46,684 47,037 +2 United States 19,552 20,670 +1 Europe 11,461 9,874 -8 Japan 3,691 3,720 +14 International 11,980 12,773 +8 CER-Constant Exchange Rates; * Geographical sales split shown here does not represent operational organization Roche 145

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