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Investor Presentaiton

mezigdomide (CELMOD) Indication Phase/Study # of Patients 2L+ MM Phase III SUCCESSOR-1 1 N = 810 Oncology Hematology Cell Therapy Immunology Cardiovascular - Mezigdomide 0.3, 0.6, 1.0 mg + bortezomib 1.3 mg/m2ª + dex 20 mg (MeziVd) • Pomalyst 4 mg + bortezomib 1.3 mg/m2a + dex 20 mg - (PVD) • Design Endpoints Status CT Identifier Primary: PFS Key secondary: OS • Recruiting Projected data readout 2026 NCT05519085 ll Bristol Myers Squibb Q3 2023 Results a BIW dosing; b QW dosing 2L+ MM Phase III - SUCCESSOR-2 N = 575 Mezigdomide 0.3, 0.6, 1.0 mg + carfilzomib 56 mg/m2b + dex 40 mg b - (Mezikd) Carfilzomib 56 mg/m2a + dex 20 mga - (Kd) Primary: PFS Key secondary: OS Recruiting Projected data readout 2026 NCT05552976 Not for Product Promotional Use 39
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