Orthofix Investor Presentation Deck

Combination of Companies Individually Well Positioned for Growth 3-Year Revenue Growth Drivers Orthofix Drivers to Low Double-Digit Growth DD Spine Fixation growth from 3-5 product and procedure launches per year and continued penetration into emerging markets Continued DD growth in BGT Fracture driven by recent AccelStim launch, future product launches and increasing channel investments HSD Orthopedics growth driven by channel expansion and further product launches expanding on our leading TrueLok and Fitbone platforms HSD Biologics growth through expanded portfolio and innovation Motion preservation portfolio enhancements for outpatient procedures and benefits of continued market momentum ORTHOFIX®™ SeaSpine. HSD: High-single-digit DD: Double-digit 22 SeaSpine Drivers to Sustain High-Teens Growth Continued share taking at >5x market growth in spinal implants and biologics from 45+ product launches since 2018 Onboard additional transformative and exclusive distributor partners Higher product utilization per procedure from more complete portfolio Increased participation in higher-revenue-per-case complex and deformity procedures from upcoming full commercialization of Mariner Adult Deformity platform Enabling Technologies growth from recent full commercial launch of MIS module and higher conversion of revenue earnout arrangements 8

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