Avantor Results Presentation Deck

M&A and leverage update Masterflex Ritter RIM Bio Total Revenue Adj. EBITDA Adj. EPS M&A CONTRIBUTION¹ FY 2022 $232M $151M $10M $393M Navantor™ $136M $0.05 1. Masterflex: Strong customer demand despite tubing destocking Ritter: Commercial synergy plans gaining momentum RIM Bio: Successful technology transfer for 2-D and 3-D bags Long-term target: 2X-4X Interest expense 4.2X YE 2021 $217M LEVERAGE UPDATE -0.5X 3.7X YE 2022 $266M Financial contribution from 3 entities acquired in 2021 (Masterflex, Ritter, RIM Bio). Includes legacy sales through Avantor channel. Includes all contributions from these entities regardless of inorganic vs. organic split. - Controlled interest expense despite rising rates in 2022 Deleveraging remains a top priority Significant M&A capacity to augment proprietary growth 8

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