AstraZeneca Results Presentation Deck slide image

AstraZeneca Results Presentation Deck

AstraZeneca: 2022-2025 Industry leading double-digit growth Durable growth drivers through 2025 including multiple blockbuster-medicines Oncology SIMFINZIⓇ durvalumab Injection for Intravenous Use 50 mg/ml CALQUENCE® (acalabrutinib) 100 mg capsules Lynparza® olaparib tablets 150 mg TAGRISSOⓇ osimertinib ENHERTU fam-trastuzumab deruxtecan-nxki 20 mg/mL INJECTION FOR INTRAVENOUS USE CVRM 19.0 farxiga (dapagliflozin) 5mg & 10mg LOKELMA sodium zirconium cyclosilicate powder for oral suspension R&I Fasenra (benralizumab) injection 30 mg BREZTRI AEROSPHERE® (budesonide 160 mcg. glycopyrrolate 9 mcg and formoterol fumarate 4.8 mcg) Inhalation Aerosol TEZSPIRE™ (tezepelumab-ekko) in 210 mg V&I EVUSHELD tixagevimab, cilgavimab Vaxzevria COVID-19 Vaccine (ChAdOx1-S [recombinant]) Rare Disease ULTOMIRIS [ravulizumab-cwvZ) injection for intravenous use SOLIRIS (eculizumab). Injection for Intravenous Use 300 mg/30 mL vial Strensiq (asfotase alfa) 40, for injection mg/mL Rare 17% R&I 16% Other 9% Diversification of disease areas and geographies Q4 2021 Total Revenue¹ Oncology 38% CVRM 20% Est. Row 13% Europe 25% 8 1. Total revenue excluding Vaxzevria. Evusheld is included in other. V&I = Vaccines and Immune Therapies. V&I will be a new reporting line within BioPharmaceuticals from Q1 2022, and will contain the following medicines, Vaxzevria, Evusheld, FluMist, Synagis and potential new medicine nirsevimab, which is being developed in collaboration with Sanofi. Emerging Markets 24% US 38% B
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