Q4 2022 Results slide image

Q4 2022 Results

Company overview Financial review 2023 priorities Appendix Expanding PluvictoⓇ development program to address significant unmet need in earlier lines and stages of prostate cancer INNOVATION Our ongoing clinical development plan for PluvictoⓇ in prostate cancer Prostate cancer incidence in US, in patients per year Early disease Local PC 283k1 BCR 41k1 Under evaluation Advanced disease nmCRPC 33k1 MHSPC 39k1 PSMAddition (mHSPC) | Primary completion 2024 Late disease mCRPC 1L 42k1 mCRPC 2L+ 27k1 PC prostate cancer. BCR biochemical recurrence. nmCRPC non-metastatic castration-resistant prostate cancer. 1. Source: Kantar 2023 US Prostate Cancer Incidence, as of 30-Jan-2023 15 Investor Relations | Q4 2022 Results PSMAfore (pre-taxane) | Primary completion 2022 VISION (post-taxane) | US/EU approval 2022 mHSPC metastatic hormone-sensitive prostate cancer. mCRPC - metastatic castration-resistant prostate cancer. ✓ NOVARTIS | Reimagining Medicine
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