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Investor Presentaiton

Research and Development Development Pipeline (as of May 15, 2023) |: Psychiatry & Neurology Area Japan U.S. : Oncology : Others DSP-9632P Phase 1 (Levodopa-induced dyskinesia in Parkinson's disease) DSP-0187 (Narcolepsy) DSP-0378 (Dravet syndrome, Lennox- Gastaut syndrome) DSP-3905 (Neuropathic pain) SEP-378614 (To be determined) SEP-380135 (To be determined) DSP-0038 (Alzheimer's disease psychosis) DSP-3456 (Treatment resistant depression) DSP-2342 (To be determined) TP-3654 (Myelofibrosis) DSP-5336 (Acute leukemia) DSP-0390 (Glioblastoma) TP-3654 (Myelofibrosis) DSP-5336 (Acute leukemia) DSP-0390 (Glioblastoma) TP-1287 (Solid tumors) TP-1454 (Solid tumors) KSP-1007 (Complicated urinary tract infections, Complicated intra-abdominal infections) SP-101 (cystic fibrosis) Phase 2 EPI-589 (ALS/Investigator-initiated study) Allo iPS cell-derived products (Parkinson's disease/ Investigator-initiated study) EPI-589 (Parkinson's disease/ALS) ulotaront (SEP-363856) (Parkinson's disease psychosis) rodatristat ethyl (Pulmonary arterial hypertension) URO-902 (Overactive bladder) Revisions since the announcement of January 2023 are shown in red Phase 3 ulotaront (SEP-363856) (Schizophrenia) ulotaront (SEP-363856) (Generalized anxiety disorder)* SEP-4199 (Bipolar I depression) ulotaront (SEP-363856) (Schizophrenia) ulotaront (SEP-363856) (Adjunctive major depressive disorder)* ulotaront (SEP-363856) (Generalized anxiety disorder)* SEP-4199 (Bipolar I depression) GEMTESAⓇ (vibegron) (New indication: OAB in men with BPH) NDA submitted China ulotaront (SEP-363856) (Schizophrenia) vibegron (Overactive bladder) *Phase 2/3 study lefamulin (Bacterial community-acquired pneumonia) © Sumitomo Pharma Co., Ltd. All Rights Reserved. 16
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