Q4 2021 Results slide image

Q4 2021 Results

Participants Company overview Pharmaceuticals Oncology Financial review Conclusion Appendix Expect to grow sales 4%+ CAGR 2020-2026 Illustrative Group sales USD billion, cc -9 TasignaⓇ LucentisⓇ XolairⓇ Without any pipeline contribution ~+1.5% CAGR CC LeqvioⓇ3 Lu-PSMA-617 ScemblixⓇ3 Other pipeline CosentyxⓇ KesimptaⓇ KisqaliⓇ ZolgensmaⓇ SandostatinⓇ GilenyaⓇ AfinitorⓇ PiqrayⓇ Sandoz EntrestoⓇ ~+5% CAGR CC if Entresto LoE beyond 20262 +4% CAGR CC 2020 IM Core Margin 35% Future Gx impact up to 20261 In-market growth drivers / Base business IM Division pipeline probabilized Excludes potential impact from US healthcare reform. Compared to R&D Day 2021, removed Ligelizumab in CSU. Votrient. 2. For internal forecasting purposes we do not expect Gx in US at least until 2025. 3. Approved in US. 2026 IM Core Margin High 30s 1. Estimated based on relevant patents; further extensions possible. Additional products include Promacta, Q-Family and 8 Investor Relations | Q4 2021 Results ✓ NOVARTIS | Reimagining Medicine
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