Investor Presentaiton

Immunology Significant unmet medical need in lupus Complex Disease • Chronic auto-immune disorder of widespread inflammation leading to end- organ damage and death Impact on QoL due to multiple associated comorbidities (i.e., infections, CV disease) • LPA₁ Sotyktu CD19 NEX T Current Treatment Landscape Few approved branded therapies • Current options have limited efficacy • Many therapies require repeated injections Significant Need: Opportunity for patients to have a novel, oral, effective medicine Ill Bristol Myers Squibb™ Not for Product Promotional Use 61

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