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Reimagining Medicine

Company overview Innovation: Pipeline overview Financial review 2023 priorities Appendix Innovation: Clinical trials Abbreviations Novartis pipeline in registration Solid Tumors Code Name VDT482 tislelizumab Mechanism PD1 inhibitor DRB436 Tafinlar+ MekinistⓇ BRAF inhibitor + MEK inhibitor Indication(s) 2L ESCC Non-small cell lung cancer HGG/LGG, pediatrics Immunology Code Name Mechanism AIN457 CosentyxⓇ IL17A inhibitor IGE025 XolairⓇ IgE inhibitor 1. Approved in US. 56 Investor Relations | Q4 2022 Results Indication(s) Hidradenitis suppurativa Psoriatic arthritis (IV formulation) Axial SpA (IV formulation) Auto-injector Cardiovascular Code LCZ696 Name Entresto® 1 lead indication Lead indication Mechanism Indication(s) Angiotensin receptor/neprilysin Congestive heart failure, pediatrics1 inhibitor NOVARTIS | Reimagining Medicine
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