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Investor Presentaiton

Key Business Performance ✓ Real-world RemsimaⓇ SC switching data has been presented at UEGW 2022 RemsimaⓇ SC ✓ Infliximab levels significantly increased post switch to RemsimaⓇ SC at 3m & remained high to 12m ✓ According to the survey, 77% of patients preferred using RemsimaⓇ SC over Infliximab IV Infliximab PK levels of RemsimaⓇ SC switching patients Serum infliximab levels, μg/dl 20 10 H H Baseline 3m 6m 12m Patient satisfaction survey after switching to RemsimaⓇ SC Strongly Disagree (6%) Disagree (6%) Neutral (11%) Strongly Agree (53%) Agree (24%) Source: Philip J Smith et al Efficacy and Safety of Elective Switching From Intravenous to Subcutaneous Infliximab (Ct-P13): A Multi-Centre Cohort Study, Journal of Crohn's and Colitis, 2022;, jjac053, https://doi.org/10.1093/ecco-jcc/jjac053 Investor Relations 2022 10
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