Investor Presentation H1 2023
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Investor presentation
First six months of 2023
Semaglutide 2.4 mg demonstrated superior reduction on the
other primary endpoint of body weight vs placebo
Change in body weight (%)
Clinically relevant and sustained weight loss in patients treated with
semaglutide 2.4 mg
Mean baseline body weight: 108.4 kg
S
-10
-15
-2.6
I-13.3
-20
0 4 8 12
16 20
28
36
44
52 52*
Time since randomisation (weeks)
Placebo
Key highlights
Novo NordiskⓇ
Primary endpoint:
•
Estimated treatment difference in body weight
change between semaglutide 2.4 mg and placebo of
-10.7%
Safety:
Overall, the safety profile in HFPEF patients is
consistent with previous data for semaglutide 2.4 mg
Semaglutide 2.4mg
Note: Data shown is the treatment policy estimand. *Lines are based on observed data where the value denoted after 52 weeks is estimated mean value derived based on multiple imputation
HFPEF: Heart failure with preserved ejection fractionView entire presentation