ALBRIOZA Commercial Launch

Targeted Approach Covering The Vast Majority of the U.S. Market ~2,700 potential ALS prescribers in the U.S.1 Physicians Treating ALS by Patient Volume2 shington North Dakota Montana Minnesota South Oregon Idaho Dakota . Wyoming California Nevada Utah United States • west Kansas Misurl rginia O Arizona Nein Mexico References: 1. Amylyx Internal Data; Mar. '23 2. Amylyx Internal Data; Sep '22. Texas Louisi Mississ insidy Maine Patient Volume 336-570 171-336 77-171 27-77 0-27 AMYLYX 13

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