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Investor Presentation

7 Investor presentation First six months of 2022 Novo NordiskⓇ GLP-1 performance drives Diabetes care sales growth in International Operations and Ozempic® is now the leading brand Reported Diabetes care sales and growth per IO geography Number of DKK billion ■Insulin GLP-1 Growth at CER GLP-1 patients and value market share in IO patients (millions) Class volume growth >50% 10% 4 Value market share 75% 25 53% 61.3% 60% 20 20 3 52.0% 12% Geographical regions 15 39.0% 45% 36.2% 30% 19.1% 15% 3.3% 0% May 2022 2 35% 10 -5% 25% -7% 83% 92% 1 5 1% -17% 1% 0 0 IO EMEA China ROW May 2020 May 2021 Ozempic ―dulaglutide -RybelsusⓇ -NN GLP-1 Source: Quarterly company announcement, IQVIA MAT, May 2022 (Spot rate). Note that the market share and patient numbers are based on countries with IQVIA coverage. GLP-1 market volume growth is calculated as a 12-month MAT IO: International Operations; NN: Novo Nordisk; EMEA: Europe, Middle East and Africa; China: Mainland China, Hong Kong and Taiwan; Row: Rest of World GLP-1 patients -VictozaⓇ
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