First Quarter 2018 Investor Presentation

Investor Presentation First three months of 2018 Slide 61 Strong GLP-1 volume growth in all regions Regional GLP-1 volume growth North America Region China Region Europe Region J&K 70% 60% 50% 40% 30% 20% 10% 0% Feb 2015 Regional GLP-1 volume market split Region Europe Region J&K Region AAMEO Region LATAM North America Region China - World 100% 80% 60% J&K: Japan & Korea; AAMEO: Africa, Asia, the Middle East and Oceania; LATAM: Latin America Note: Data is sensitive to changes in IMS data collection and reporting methodology Source: IQVIA monthly MAT Feb, 2018 volume figures changing diabetes® 22% 40% 20% 0% Feb 2018 Feb 2015 Region AAMEO Region LATAM 3% 8% 1% 4% 38% J&K: Japan & Korea; AAMEO: Africa, Asia, the Middle East and Oceania; LATAM: Latin America Note: Data is sensitive to changes in IMS data collection and reporting methodology Source: IQVIA monthly MAT Feb, 2018 volume figures 46% Feb 2018 novo nordisk

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