Avantor Results Presentation Deck

4 Regional Core Organic Growth & Adjusted EBITDA (Annual) (Dollars in millions) Navantor™ Americas GAAP consolidated net sales Core organic growth COVID Impact Organic growth M&A Impact FX Impact Reported net sales growth Adjusted EBITDA (non-GAAP) Adjusted EBITDA margin Adjusted EBITDA margin growth (-bps) Europe GAAP consolidated net sales Core organic growth COVID Impact Organic growth M&A Impact FX Impact Reported net sales Adjusted EBITDA (non-GAAP) Adjusted EBITDA margin Adjusted EBITDA margin growth (-bps) AMEA GAAP consolidated net sales Core organic growth COVID Impact Organic growth M&A Impact FX Impact Reported net sales growth Adjusted EBITDA (non-GAAP) Adjusted EBITDA margin Adjusted EBITDA margin growth (-bps) FY2020 $3,731 $ $45 $119 $164 $0 -$17 $147 $802 21.5% 190 bps FY2020 $2,287 $ $25 $123 % 1.3% 3.3% 4.6% 0.0% -0.5% 4.1% $148 $0 $37 $185 $ $1 $24 $25 $0 -$3 $22 % 1.3% 5.8% 7.1% 0.0% 1.7% 8.8% $398 17.4% 50 bps FY2020 $375 % 0.2% 6.9% 7.1% 0.0% -0.9% 6.2% $80 21.3% -170 bps $ $330 121 $451 35 20 $506 FY2021 $4,237 $978 23.1% 160 bps $ $176 29 $ $75 (13) $62 23 11 $96 % 8.8% 3.2% 12.1% 1.0% 0.5% 13.6% FY2021 $2,677 $206 85 99 $391 % 7.7% 1.3% 9.1% 3.7% 4.2% 17.1% $539 20.1% 270 bps FY2021 $471 % 20.0% -3.4% 16.6% 6.2% 2.8% 25.6% 114 24.2% 290 bps FY2022 $4,471 $ $260 (145) $115 133 (14) $234 $1,077 24.1% 100 bps FY2022 $2,517 $ $148 ($124) $24 % 6.1% -3.4% 2.7% 3.1% -0.3% 5.5% $92 ($276) ($161) % 5.5% -4.6% 0.9% 3.4% -10.3% -6.0% $524 20.8% 70 bps $ $33 $4 $37 $43 ($27) $53 FY2022 $525 % 7.0% 0.8% 7.8% 9.1% -5.6% 11.3% $142 27.0% 280 bps Note: the sum of Americas, Europe, and AMEA does not equal Total, Avantor. Does not include corporate-level expenses 7

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