Investor Presentation Full Year 2017 slide image

Investor Presentation Full Year 2017

Investor Presentation Full year 2017 Slide 94 Strong growth among long-acting haemophilia B products as Refixia®/RebinynⓇ is set for launch in the EU and the USA Reported recombinant FIX sales Sales (USD million) 1,200 1,000 800 600 400 200- 0 2011 Benefix® AlprolixⓇ CAGR: +10% IdelvionⓇ • 2016 . RefixiaⓇ/RebinynⓇ launched in first countries Launched in the first EU countries in 2017, US launch expected in the first quarter of 2018 RefixiaⓇ/RebinynⓇ offers a unique clinical profile that brings factor levels into the non-haemophilia range for adults and adolescents • Dialogue ongoing with the FDA and EMA to establish path forward to obtain routine prophylaxis indication in the USA and complete paediatric indication in Europe to include children younger than 12 years old FIX: Coagulation factor IX Source: Company reports (Does not include RixubisⓇ as sales are not reported separately) changing diabetes® FDA: US Food and Drug Administration; EMA: European Medicines Agency rFIX: Recombinant coagulation factor IX novo nordisk
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