Investor Presentation - First Six Months of 2021

86 Investor presentation First six months of 2021 Growth momentum has increased driven by demographics and the Market Fit approach International Operations is diverse and covers 190 markets 14% 430M live with diabetes 12% 10% 570M 8% live with obesity 6% 4% IO's share of revenue YTD 2021 2% NAO 45% ΙΟ 55% Novo NordiskⓇ Historic growth has been in the range of 4-6% Growth momentum has benefitted from the Market Fit approach 30% 10% 20% الس 10% 0% 2013 2020 May Market Fit approach 2018 Growth rate range introduced NAO: North America Operations; IO: International Operations; Share of Growth not depicted due to high numbers; FY: Full Year NN Diabetes market share Market growth NN Diabetes growth 24% 9% 2% May 2021

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