Investor Presentaiton

VENTASⓇ Ventas's Long-Term TSR Outperformance, With Recent TSR Leading the Recovery; In-Line Medium-Term TSR Impacted by Pandemic Av 2022 Year-to-Date One-Year Total Shareholder Return Three-Year Annualized Five-Year Annualized Ten-Year Annualized Since 1999 Annualized (1) Top performer of the 16 Outperformance driven One- YTD by strong senior housing constituents in the Nareit HC Index Year recovery currently Medium- Modest underperformance in medium-term periods driven by the severe and outsized impact of the Term COVID-19 pandemic on senior housing, which comprises roughly half of Ventas's portfolio Since 1999 underway +23% +21% I.I A VENTAS +5% Index +15% +8% +7% +7% +6% +4% +4% Exceeds Nareit HC Index, as well as MSCI U.S. REIT Index's annualized figure of 11% and S&P 500's 7% +20% +14% Nareit HC A VENTAS Nareit HC Index A VENTAS Nareit HC Index A VENTAS Nareit HC Index A VENTAS* Nareit HC Index A VENTAS Nareit HC Index Source: (1) FactSet as of March 25, 2022. Annualized TSR since December 31, 1999. 11

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