Corporate & Investor Presentation

Opportunity to shift care from hospital to home . Healthcare costs are on the rise Combining non-invasive ventilation (NIV) with home oxygen therapy (HOT) - - Reduces hospitalization and mortality by 51% Increases time to hospital readmission or death by ~90 days JAMA® The Journal of the American Medical Association Admission-free Survival % 100- 80 60 40 20 20 Admission-free survival by treatment arm over one year Adjusted hazard ratio, 0.49 (0.31-0.77); P=.002 Home Oxygen Plus Home NIV Home Oxygen Alone Combination of HOT with NIV reduced hospital readmissions by 58.3% Combination of therapies provided improved patient quality of life and saved >$50k per quality of life adjusted year 01 0 2 4 6 8 10 12 Time (months) 1 P. Murphy et al., Effect of Home Noninvasive Ventilation With Oxygen Therapy vs Oxygen Therapy Alone on Hospital Readmission or Death After an Acute COPD Exacerbation. A Randomized Clinical Trial, JAMA .Published online May 21, 2017. doi: 10.1001/jama.2017.4451. 48 2022 ResMed | Corporate & Investor Presentation - updated 27JAN22 ResMed

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