Investor Presentation Q1-Q3 2020

85 Investor presentation First nine months of 2020 Insulin market size and volume market share in EMEA Insulin market share and market size (DKK billion) Total 47% Long- acting 38% Fast- 56% 11 acting 71% Premix 4 18 Novo Nordisk® Market growth A Market share Insulin volume: market share 80% 37 3% +1.0% 12% 10% 60% 6% +1.7% 8% 47% 6% 40% 4% 4% +0.9% 2% 4% 20% -0.6% +1.6% 0% Aug 2017 -8% -0.7% NN market share 0% -2% -4% Aug 2020 44% Human 4 Novo Nordisk Competitors Source: IQVIA, Aug 2020, LHS graph - Value, RHS Graph - Volume, MAT, Europe, Middle East & Africa, Share of growth not depicted due to too high numbers; NN: Novo Nordisk -Market growth (right axis) NN growth (right axis)

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