Retail Banking Performance Update

Brazil (Constant EUR mn) Change Change Q1'21 Q2'21 Q3'21 Q4'21 Q1'22 Q2'22 Q3'22 Q4'22 Q4'22/Q3'22 2021 2022 2022/2021 Net interest income 2,164 2,253 2,368 2,462 2,311 2,197 2,188 2,205 +0.8% 9,248 8,901 -3.7% Net fee income 769 821 791 826 801 830 789 876 +11.0% 3,206 3,296 +2.8% Gains (losses) on financial transactions and other 132 74 117 7 144 235 210 125 -40.6% 330 714 +116.0% Total revenue 3,066 3,149 3,275 3,295 Operating expenses (879) (916) (983) (1,025) 3,256 (1,003) Net operating income 2,186 2,233 2,292 2,270 2,253 2,276 2,156 3,263 3,186 3,205 (987) (1,030) (1,160) 2,045 +0.6% 12,785 12,910 +1.0% +12.6% (3,803) (4,180) +9.9% -5.1% 8,981 8,730 -2.8% Net loan-loss provisions (668) (794) (864) (866) (919) (1,136) (1,122) (1,240) +10.6% (3,191) (4,417) +38.4% Other gains (losses) and provisions (117) (32) (102) (121) (123) (37) (20) (78) +284.2% (372) (259) -30.4% Underlying profit before tax 1,402 1,407 1,326 1,284 1,212 1,102 1,014 727 -28.3% 5,419 4,055 -25.2% Underlying consolidated profit 758 803 740 735 755 794 716 557 -22.3% 3,036 2,822 -7.0% Underlying attributable profit 682 726 657 662 677 715 643 510 -20.6% 2,727 2,544 -6.7% Santander 49

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