Benevolent Platform Precision Medicine slide image

Benevolent Platform Precision Medicine

Significant progress across all aspects of the business since mid-2020 OOOO Pharma partnerships → Baricitinib; 38% reduction in mortality v SOC. Eli Lilly investment → AstraZeneca; continued delivery, 1st target selected for CKD Pipeline Progress → Phase 1b for Atopic Dermatitis progressing well. Completion by mid-2022 →IND-enabling studies started for novel Ulcerative Colitis asset (PDE10) Platform Enhancements → Mechanism mapping to better represent disease → Improved capacity to ingest human patient level data and genetics at scale Business Model → Ambition to take assets through to commercialisation ourselves including, PDE10 for UC People → Building a world-class Board (Dr. Francois Nader, Dr. John Orloff, Sir Nigel Shadbolt) → Investing in people to support a scaling pipeline (>80 recruited in last year) Al Benevolent 74
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