Investor Presentation First Nine Months of 2022 slide image

Investor Presentation First Nine Months of 2022

67 Investor presentation First nine months of 2022 In STEP 4, people treated with semaglutide had a superior weight loss of up to 18.2% STEP 4 showed significantly greater weight loss post run-in than placebo % change in body weight Randomisation Data from STEP 4 0 -2 -4 -6 -8 ≈ 46% -10 I I Placebo: -5.2% -12 -10.5% -14 -16 I -18 I Semaglutide: -18.2% -20 0 4 8 12 16 20 24 28 36 44 52 60 68 88 Time since initiation (weeks) Change in body weight in % depicts observed means since time of randomisation; trial product estimand; BMI: body mass index • • Average age 46 79% women Average BMI - 38.4 kg/m² Novo NordiskⓇ Trial highlights that obesity is a chronic disease requiring sustained treatment Improvements on a panel of cardiovascular risk markers
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