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Investor Presentaiton

Revenue Tops 5.39B RMB with Net Profit of 546M RMB Revenue BD ៣ ເຮົາ Pipeline Commercial Capacity 5.39B RMB Commercialization 4 BD Achieved sustainable and profitable growth from strong sales team & effective sales management Over RMB 100M average monthly sales in China from HLX10 (Serplulimab, PD-1) since March 2023; approval of new indication ESCC HLX02 (trastuzumab) average monthly sales in China exceeding RMB 200M since Q2 2023 with a lower expense ratio . HLX10 out-licensed to Intas in Europe 50+ countries and India, with upfront payment up to EUR 42M1, a total payment up to EUR 185M HLX10 out-licensed to Kalbe in the MENA, with upfront payment of USD 7M and a total amount up to USD 665M² In-licensed exclusive rights of Lasofoxifene (SERM) in China from Sermonix for HR+/HER2- breast cancer 50+ R&D The clinical data of HLX10 for 1L sqNSCLC phase III (ASTRUM-004) was presented in WCLC HLX10+ chemo combo approved for 1L ESCC in China HLX42 (EGFR ADC) for TKI failed NSCLC was granted FDA Fast Track Destination (FTD) and entered into phase I HLX43 (PD-L1 ADC), a potential first-in-class product, entered into phase I • 48KL Manufacturing Xuhui Site and Songjiang 1st Plant have passed EU GMP inspection of production areas for HLX10 Xuhui Site passed Indonesia's BPOM (PIC/S member country) inspection of HLX10 production lines Xuhui Site passed Brazil's ANVISA (PIC/S) GMP compliance inspection for HLX01 and HLX02 Operating Cash Flow 1.05B RMB 1. The first part of upfront payment EUR 26M will be paid upon on agreement effective date; and the second part of the upfront payment EUR 16M will be paid when the EMA issues positive 3 opinion (210th day of the evaluation procedure) on the 1L treatment for ES-SCLC; 2. The scope of the sales milestone payments will also include the previously authorized Southeast Asia region, and the total sales milestone payments for the two authorizations will be no more than US$650M • · Financial Total revenue reached RMB 5.39B in 2023, 67.8% YoY growth Total product sales reached RMB 4.55B, 70.2% YoY growth Net operating cash inflow of RMB 1.05B Net profit reached RMB 546M, and net profit rate was 10.1% 2 Henlius
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