Benevolent Platform Precision Medicine

Target Validation: Confirming the hypotheses ° 00 00 00 1. Data Preparation 2. Target Prediction 3. Target Triage 4. Target Validation Focus and curate a biological question Graph Completion Human Queries 1 2 3 4 MM Reinforcement Learning 'omics ☐ ☐ ☐ ☐ Target Safety Drugs? Metadata Score Tgt1 Safe Tgt2 Unsafe No Partial OPC, GCNN 0.71 SQT 0.65 Tgt3 Safe Yes OPC, CROM 0.51 Tgt4 PhaseII Offtgts OPC 0.49 Model fleet predictions Prediction evaluation Equip experts with data Triage predictions Perform Assays Analysis & retro 1. Disease Data Package 2. Predictions Package 3. Hypothesis Package 4. Validated Hypothesis Package Benevolent 23 ΑΙ

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