Fourth-Quarter and Full-Year 2019 Orphan and Rheumatology Segment Results
Gout: A Systemic Disease Often Associated with Multiple Negative Consequences
•
Gout
Most common inflammatory arthritis (1)
Characterized by multiple comorbidities,
including chronic kidney disease and
hypertension
Systemic disease; uric acid deposits can
occur almost anywhere in the body
9.5M
U.S.gout patients;
growing low-single digits (2)
3.5M
Uncontrolled Gout
Chronic gout refractory (unresponsive)
to conventional therapies
U.S. gout patients
seeking treatment (2)
~100K
Uncontrolled
gout patients
~4K
Treated with
(1) Zhu Y, Pandya BJ, Choi HK.
(2) Prevalence of gout and hyperuricemia in the U.S. general population: The National Health and Nutrition Examination Survey (NHANES) 2007-2016. Arthritis Rheum. 2019 Jun;71(6):991-999.
HI HORIZON
KRYSTEXXA in 2019
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