Investor Presentaiton

Laboratory tests ■ Screening test - IgG & IgM (By itself is not reportable to MHO) RPR - Rapid Plasma Reagin (non-treponemal): Quantitative ■ Guides treatment and re-infection for previous cases ■ NR, 1:1, 1:2, 1:4, 1:8, 1:16, 1:32, 1:64, 1:128, 1:256, 1:512,.... ■ TPPA - T. pallidum Particle agglutination assay Treponemal test (specific for T. pallidum antibody) ■ Reportable (Reactive or Indeterminate) ■ Remains "Reactive" for life Direct Detection Test - Sent to NML, Winnipeg ■ PCR - Polymerase chain reaction - UTM swab taken from "chancre" ■ Tests for genes: polA, bmp, tpp47 Saskatchewan Health Authority

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