Diagnostics Solutions Strategic Priorities slide image

Diagnostics Solutions Strategic Priorities

Leading coronary artery disease Setting new standards of care in diagnosing heart attacks Elecsys® Troponin T-high sensitive (TnT-hs) test New data on cardiac risk in non-cardiac surgery 1 hour decision algorithm 1 HOUR RULE-OUT OBSERVE 57% 25% RULE-IN 18% 5 NSTEMI 158 NSTEMI 572 NSTEMI TRIAGE Shortened hospital stay in suspected heart attack leading to reduced clinical costs 1,2 . • Algorithm confirmed in interventional studies and included in treatment guidelines3,4,5,6 • 100 million chest pain patients treated globally All-Cause Mortality 30%- 15% Preop. TnT-hs >14 ng/L e.g. Prediction Preop. TnT-hs <14 ng/L Identify and prevent 0% - 0 1 2 3 2 Survival time in Years TnT-hs test able to predict heart attack risk and mortality in non-cardiac surgeries • > 80% of myocardial injuries after non-cardiac surgery are clinically asymptomatic • 300 million non-cardiac surgeries globally6,7 1 Twerenbold, R et al. J Am Coll Cardiol. 2018, 72: 620; 2 Ambavane A et al., PLoS One. 2017; 12(11): e0187662; 3 Chew D et al, Circulation. 2019,140:1543; 4 Stoyanov KM et al, Eur Heart J Acute Cardiovasc Care. 2020, 9:39; 5 Puelacher C et al. Circulation. 2018, 137:1221; 6 Devereaux PJ et al. JAMA 2017, 317:1642; 7 Nagele P et al, Am Heart J. 2013, 166: 325 57 Roche
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