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Investor Presentaiton

Novo Nordisk Annual Report 2023 FINANCIALS Introducing Novo Nordisk Strategic Aspirations Risks Management Consolidated statements Additional information 2023 performance and 2024 outlook STRATEGIC ASPIRATIONS 2025 1. Deliver solid sales and operating profit growth 2. Drive operational efficiencies across the value chain to enable investments in future growth assets 3. Deliver free cash flow to enable attractive capital allocation to shareholders Financial performance Sales increased by 31% measured in Danish kroner and by 36% at CER to DKK 232,261 million in 2023. Novo Nordisk's 2023 sales and operating profit performance measured at CER were within the ranges provided in November 2023. The free cash flow, effective tax rate, capital expenditure as well as depreciation, amortisation and impairment losses were all in line with the guidance. FINANCIAL PERFORMANCE (DKK billion) North America Operations net sales O Growth at CER 300 250 International Operations net sales 16% 200 14% 7% 150 100 50 36% 0 2020 2021 2022 2023 Geographic sales development Sales in North America Operations increased by 50% measured in Danish kroner and by 54% at CER. Sales in International Operations increased by 11% measured in Danish kroner and by 16% at CER. Sales in EMEA increased by 15% measured in Danish kroner and by 17% at CER. Sales in Region China increased by 3% measured in Danish kroner and by 11% at CER. Sales in Rest of World increased by 11% measured in Danish kroner and by 15% at CER. Sales development across therapeutic areas Sales in Diabetes care increased by 24% measured in Danish kroner and by 29% at CER. Sales of Obesity care products, WegovyⓇ and SaxendaⓇ, increased by 147% measured in Danish kroner and by 154% at CER. Sales of Rare disease products decreased by 16% measured in Danish kroner and by 15% at CER. In the following sections, unless otherwise noted, market data are based on moving annual total (MAT) from November 2022 and November 2023 provided by the independent data provider IQVIA. Diabetes care Sales in Diabetes care increased by 24% measured in Danish kroner and by 29% at CER to DKK 173,466 million driven by growth of GLP-1-based products. Novo Nordisk has improved the global diabetes value market share over the last 12 months to 33.8% from 31.9%. The market share increase was driven by market share gains in both North America Operations and International Operations. GLP-1-based therapy for type 2 diabetes Sales of GLP-1-based products for type 2 diabetes (Rybelsus®, OzempicⓇ and VictozaⓇ) increased by 48% measured in Danish kroner and by 52% at CER to DKK 123,132 million. The estimated global GLP-1 share of total diabetes prescriptions has increased to 6.0% compared with 4.5% 12 months ago. Novo Nordisk continues to be the global market leader in the GLP-1 segment with a 54.8% value market share. RybelsusⓇ sales increased by 66% measured in Danish kroner and by 71% at CER to DKK 18,750 million. Sales growth was driven by North America Operations as well as EMEA and Rest of World. OzempicⓇ sales increased by 60% measured in Danish kroner and by 66% at CER to DKK 95,718 million. Sales growth was driven by both North America Operations and International Operations. Sales growth 34
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