Novo Nordisk Investor Presentation - First Nine Months of 2016

Investor presentation First nine months of 2016 Slide 37 The insulin market is comprised of three segments Insulin action profiles Global insulin volume market by segment CAGR volume¹: 4.6% CAGR value¹: 20.4% tMU Fast-acting 450 400 350 40% Long-acting 300 37% Premix 250- 26% 200 Premix 29% 150 100 Long-acting 34% Fast-acting 34% 50 0 6:00 10:00 14:00 18:00 22:00 2:00 6:00 Aug 2011 Aug 2016 ↑ 1 Time of day Breakfast Lunch Dinner changing diabetes® 1 CAGR for 5-year period. Value in DKK Note: US trend data reflect changes to IMS data collection coverage and methodology as of January 2012 Source: IMS Monthly MAT volume and value August (DKK) figures novo nordisk

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