Full Year 2023 Investor Presentation

147 Investor presentation Full year 2023 Currency impact on Novo Nordisk's P/L Operational currency impact All movements in currencies will directly impact the individual reported functional lines of the Novo Nordisk's P&L statement The currency effect on e.g. operating profit growth is the difference between the reported growth and the operating profit growth at CER Key currencies account for around 80% of the total currency exposure No hedging effects are included in the operating profit Sensitivity table gives an indication of gain/loss of a 5% immediate change in exchange rates compared to exchange rates on announcement day DKK million Income statement Net sales Cost of goods sold Gross profit Operating profit Note: Example is based on Annual Report 2023 Novo NordiskⓇ 2023 2022 232,261 176,954 (35,765) (28,448) 196,496 148,506 Financial currency impact All gain/losses from hedging contracts are included in the financial income/expenses Hedged cover for key currencies: • USD 12 months Sales and distribution costs (56,743) (46,217) • JPY 12 months Research and development costs Administrative costs (32,443) (24,047) • CAD 9 months (4,855) (4,467) • GBP 0 months :Other operating income and expenses 119 1,034 CNY 12 months 102,574 74,809 Financial income 2,945 239 • Financial expenses (845) (5,986) Profit before income taxes 104,674 Income taxes (20,991) Net profit 83,683 69,062 (13,537) 55,525 Earnings per share Basic earnings per share (DKK) 18.67 12.26 Diluted earnings per share (DKK) 18.62 12.22 Hedging is primarily performed with the use of forward contracts Net financials includes hedging gain/loss including the cost of hedging and the effect from currency gain/losses of balances in non-hedged currencies Hedging costs are the interest rate differentials between DKK and hedged currencies

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