2022 Financial Outlook and Strategic Framework

15% Adj. EPS CAGR Proven ability to grow and innovate through change Decade-long track record of average annual adjusted EPS growth greater than ADJUSTED EPS $25 $20 our 10%-13% target MAJOR EVENTS CIGNA EVENTS © 2022 Cigna $15 $10 $5 $- 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 ACA Individual Public COVID-19 Enacted Mandate Upheld Exchanges Pandemic HealthSpring Acquisition Launched Anthem Merger Proposal Express Scripts Began Evernorth Launch Group Divestiture Acquisition - Cigna. 8

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