2022 Highlights and ESG Progress

...led to increased profitability, shareholder remuneration and returns Profitability + EPS growth TNAVps + Cash DPS € cents ROTE EPS 53.9 13.4% 43.8 12.0% +23% YOY 2021 2022 2021 2022 € per share 4.37 4.12 +6% YOY 2021 2022 2022 includes €0.11 of cash dividends² Cash DPS1 growth: +16% YoY In the last two years, we have repurchased 5% of our outstanding shares³ Santander (1) Our 2022 shareholder remuneration policy is c.40% payout split in approximately equal parts (cash and share buybacks). Cash DPS estimated as 20% of the profit for the year. Implementation of the shareholder remuneration policy is subject to future corporate and regulatory decisions and approvals. (2) Including the cash dividends per share paid in May 2022 and November 2022. (3) Includes share buybacks completed in Nov-21, May-22 and January-23. 7

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