Investor Presentaiton

Investor Presentation First six months of 2018 Slide 39 The insulin market is comprised of three segments 6:00 10:00 ↑ Breakfast changing diabetes® Insulin action profiles tMU 600 Global insulin volume market by segment CAGR volume¹: 4.8% CAGR value¹: 15.3% Fast-acting 500 35% 400 Fast-acting 34% Premix 300 25% Premix 29% 200- Long-acting 100 37% Long-acting 40% 0 14:00 18:00 22:00 2:00 6:00 ↑ ↑ Time of day May 2013 May 2018 Lunch Dinner 1 CAGR for 5-year period. Value in DKK Source: IQVIA monthly MAT volume and value May 2018 (DKK) figures novo nordisk

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