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Investor Presentaiton

B-cell function Investor Presentation First nine months of 2018 Slide 49 Insulin is the ultimate care for people with diabetes Progression of type 2 diabetes and treatment intensification Distribution of patients and value across treatment classes Diet and exercise OAD: Oral anti-diabetic changing diabetes Time OAD GLP-1 100% Insulin GLP-1 80% 37% 68% 60% 14% 40% Insulin 5% 49% 20% 27% 0% Patients Value Note: Patient distribution across treatment classes is indicative and based on data for the USA, the UK, Germany and France. Value figures based on IQVIA MAT Aug, 2018 Source: IQVIA PharMetrix claims data, IQVIA disease analyser, IQVIA MIDAS OAD novo nordisk
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