Investor Presentation First Nine Months of 2022

149 Investor presentation First nine months of 2022 Attractive capital allocation to shareholders DKK billion 50 40 40 Annual cash return to shareholders Capital allocation Novo NordiskⓇ 24 24 • Return of free cash flow through both share buy-backs and dividends • For 2022, the interim dividend of DKK 4.25 per share was paid in August 2022 • The final dividend for 2022 will be paid in March 2023 • Ongoing DKK 24 billion share repurchase programme for 2022 30 17 15 20 20 20 20 10 8 7 8 10 16 12 13 14 0 2022E¹ Share repurchase 2019 2020 2021 Dividend Interim dividend 1 For 2022, expected free cash flow is DKK 54-59 billion

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