ATAI Investor Day Presentation Deck

Clinical insights in cognition Symbol coding a well-established and sensitive measure in CIAS Correlates well with overall movement of MATRICS battery Observed changes larger than expected from practice Effect size in range that correlates with improvement in work/school performance Immediate word recall effects similar to previous studies (20 mg) Longer duration of treatment may extend/strengthen initial findings in CIAS * Keefe, Harrison, Green, & Nuechterlein Encouraging bi-phasic trends in cognitive data atai LIFE SCIENCES | 39

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