Investor Presentation - First Six Months of 2021

132 Investor presentation First six months of 2021 Defeating diabetes starts by taking preventive measures Novo NordiskⓇ Global obesity burden is part of the cause for rising diabetes prevalence for both adults and children The global obesity burden 120m 650m Adults living with obesity Children living with obesity Bend the global obesity curve • Anti-obesity market is mainly an out-of-pocket market, but progress is being made in reimbursement for adults . • . Changing Obesity is our commitment to prevention, recognition and care within obesity novo nordisk in support of unicef UNICEF partnership to help prevent childhood overweight and obesity worldwide¹ by enhancing knowledge and awareness with initial focus on Latin America and the Caribbean Medium-term goal of enrolling >500,000 children in Latin America by 2023 1 UNICEF does not endorse any company, product, brand or service. Note: An extensive overview of specific actions taken within Cities Changing Diabetes can be found here: https://www.citieschanging diabetes.com/ • Strengthen prevention by focusing on health inequality in cities Today's challenge: Two-thirds of people with diabetes globally live in cities and it is 8 increasing Expanding the reach with engaged cities in Cities Changing Diabetes Today, 36 cities are enrolled in Cities Changing Diabetes, totalling 200+ million citizens In November 2020, Urban Diabetes Action Framework was launched, helping city practitioners to develop impactful public health interventions Launch of Prevention Accelerator inviting start-ups to submit ideas for how to predict or prevent obesity

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