Innovent Biopharmaceutical Transformation slide image

Innovent Biopharmaceutical Transformation

Building Leading Commercial Franchise with Expanding Approved and Late-stage Portfolio in Near Term Robust Late Stage Assets for Growth Oncology/Non-Oncology TA Target/Asset PD-1 (sintilimab) Product CD20 (rituximab) TYVYTⓇ HALPRYZAⓇ Status Launched Indication CHL Launched NHL TYVYT Broad Patients and Big Market TYVYTⓇ CYRAMZAⓇ IBI-362 PCSK9 达攸同® W BYVASDAⓇ VEGF/C CTLA-4 Sintilimab injection Hematology BCR/ABL (olverembatinib) NAILIKE Launched CML BCMA CART (Equecabtagene Autoleuce) IBI-326 NDA in 1H2022 MM PI3K (parsaclisib) IBI-376 49 PD-1 (sintilimab) TYVYTⓇ CYRAMZA™ PD-1 (sintilimab) TYVYTⓇ ramucirumab injection 10 mg/ml solution Lung Cancer RET (selpercatinib) ROS1 (taletrectinib) RETSEVMO® IBI-344 Pivotal Ph2 Launched Launch in 2022 Launch in 2022 FL 1L sqNSCLC; 1L nsq NSCLC Pivotal Ph2 HALPRYZAⓇ SULINNOⓇ PemazyreⓇ IL-23 Clear Unmet Olverembatinib PDE4 Need and Good RETESVMO® Opportunity 达伯华 達伯坦> BCMA CAR-T Pemazyre (tablets) ROS1/NTRK 苏立信 PI3K8* 奧爾巴尼 pivorembatinib # KRAS G12C PD-1 (sintilimab) IBI-351 Ph1 TYVYTⓇ Launched EGFR+ NSCLC RET+ NSCLC ROS1+ NSCLC KRAS+ NSCLC 1L HCC VEGF-A (bevacizumab) BYVASDAⓇ Launched 1L HCC Retevmo™ Liver Cancer VEGFR2 (ramucirumab) CTLA-4 (ipilimumab) FGFR1/2/3 (pemigatinib) CYRAMZAⓇ Launched 2L GC IBI-310 PEMAZYRE® Ph3 Launched 1L HCC PD-1 (sintilimab) PD-1 (sintilimab) 耐立克 Gastrointestinal VEGFR2 (ramucirumab) KRAS G12C CLDN18.2 TYVYTⓇ TYVYTⓇ CYRAMZAⓇ IBI-351 IBI-360;IBI-345;IBI-389 Launch in 2022 Launch in 2022 CCA 1L GC 1L ESCC Launched Ph1 Ph1 Franchise and Synergy in TAs Gynecological Metabolic PD-1 (sintilimab) CTLA-4 (ipilimumab) VEGF-A (bevacizumab) PCSK-9 (tafolecimab) GLP1/GCGR TYVYTⓇ IBI-310 BYVASDAⓇ TNFα (adalimumab) IBI-306 IBI-362 SULINNOⓇ Autoimmune IL-23 IBI-112 PDE4 (orismilast) IBI-353 Ph3 in 2023 Oncology | Metabolic | Autoimmune | Ophthalmology Ophthalmology VEGF/C (efdamrofusp alfa) IBI-302 Ph2 Innovent Confidential Copyright©2022 Innovent Pivotal Ph2 Pivotal Ph2 Launched NDA in 1H2022 Ph3 in 2022 Launched Ph3 in 2022 2L GC CRC, PC, etc. GC, PC, etc. 2L CC 2L CC OC, CC nFH, HeFH Diabetics, Obesity RA, AS, Psoriasis, PJIA, Uveitis Psoriasis; Ulcerative colitis Psoriasis; Atopic Dermatitis nAMD 17
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